My Harmony One does fine with the UMC-200.
For the most part I really like the UMC. My primary trouble is what I'm assuming to be an HDMI issue with either my TV or Dish Hopper. Occationally, every couple of days, with the UMC off, I lose all sound from the Hopper to the TV. Even when I switch cables and go directly from Hopper to TV instead of going through the UMC; the sound does not come back.

I need to completely reboot the Hopper.
The GF prefers to watch TV via the TV speakers.

The HDMI standby passthru was one of the reasons I got the UMC. I'm a bit frustrated.