In a room that size, there is a lot of space to fit two subs.

Seems like this is coming up a lot lately.
If you aren't in to taking room measurements with a program like REW, no biggy. It's a serious step, and one I've only recently started taking. If you choose to embrace the more serious side of this hobby, check it out, but you can still find success in setting up your room with other techniques.
I'm a fan of the
Subwoofer Crawl. It is crude, but uses the room's own acoustics to aid you in finding the best places to put the Subs. My own experience is that you can find some very good places, acoustically, to put the subs and not need to test. Testing will improve your overall results, but if you are an astute listener, that becomes icing on the cake.
I prefer starting from a standpoint based on Geddes technique which involves placing multiple subs strategically and asymmetrically around the room. He also says mains should be considered as LF sources... even more important if they are truly full range, but even 50-200 Hz can fall into that "LF range" amd affect the room.
The basic goal here is to activate as many room modes as possible, thus cancelling as many standing waves or cancellations as possible. This results in a smoother bass response throughout the room, thus a better listening experience over a wider range of seats.
Considering that common advice insists on front wall and/or corner placement, I found the best places in my room to be away from the front and the corners.
Every room is different!
This cannot be stressed enough.
Every room is different!
What works for one room will not necessarily work for the next. In my mind, if you have distances from LP to each Speaker, and from Speaker to Speaker, that are all at least slightly different, you will take a serious step towards aiding your battle with room acoustics.
This is my experience. YMMV (Your Mileage May Vary).