I saw a rheumatologist last year. Do you recall what blood test or other test was able to diagnose you with AS? Do you have difficulty bending your spine? Are you HLA-B27 positive?The major symptom I have is auto-immune inflammation of my eye, my left eye only, go figure. It is said by a British (?) study of AS, that 30% of AS patients had no other symptoms.\n\nMy blood tests for RF and HLA-B27 were both negative. That same British study said 90% of those AS patients had the B27 haplotype. I do not.\n\nI am not aware of any major difficulty bending my spine, or of major lower back pain, but a series of x-rays of my lower spine and pelvis joints showed enough signs of inflammation to diagnose me with AS. That was enough for the rheumatologist to make the call. I did not suffer from any of this until my 60s, clearly not juvenile onset AS.