There are theories about why one group is better than another (Sat vs Towers).
But in my reality there is utterly no advantages of Towers over Sat + Subs.
IOW, if I had to choose between either 1) Sat + Subs or 2) Towers with no subs, I would go with Option 1 unequivocally.
Bass from most towers are just lacking to me. But everyone is different.