M

Mr._Clark

Audioholic Samurai
I saw that. I also noticed the following study about the effects of even moderate alcohol consumption on the brain:

>>>Adults aged 50 and over who consumed two units (a pint of beer or a glass of wine) per day showed brain changes equivalent to two years of aging.<<<


It made me think my brain will really be toast if I get COVID, or something like that. Come to think of it, or try to think about it, I'm not really sure, actually, what I was thinking. A man has to believe in something, I believe I'll have a beer.
 
Verdinut

Verdinut

Audioholic Spartan
I saw that. I also noticed the following study about the effects of even moderate alcohol consumption on the brain:

>>>Adults aged 50 and over who consumed two units (a pint of beer or a glass of wine) per day showed brain changes equivalent to two years of aging.<<<


It made me think my brain will really be toast if I get COVID, or something like that. Come to think of it, or try to think about it, I'm not really sure, actually, what I was thinking. A man has to believe in something, I believe I'll have a beer.
That reminds me of the minute quantities of the carcinogenic nitrosamines in beer. Like you, I prefer to have a more relaxed life and I drink ¼ liter of wine almost daily rather than avoiding alcohol which is known to destroy brain cells.

Each of us has a biochemical individuality. So we don't react equally and at times quite differently to substances and medication which we consume. Let's hope at least that moderate consumption of beer and wine does not affect us until it's the time to leave our current lives.
 
mtrycrafts

mtrycrafts

Seriously, I have no life.
I saw that. I also noticed the following study about the effects of even moderate alcohol consumption on the brain:

>>>Adults aged 50 and over who consumed two units (a pint of beer or a glass of wine) per day showed brain changes equivalent to two years of aging.<<<


It made me think my brain will really be toast if I get COVID, or something like that. Come to think of it, or try to think about it, I'm not really sure, actually, what I was thinking. A man has to believe in something, I believe I'll have a beer.
I recommend getting rid of all toasters in the house, including toaster ovens. :D

So, if I don't drink that amount daily, I should be ok? Every other day? Once a week? What is safe, I wonder. No, not going to be a test subject. :D
 
panteragstk

panteragstk

Audioholic Warlord
I saw that. I also noticed the following study about the effects of even moderate alcohol consumption on the brain:

>>>Adults aged 50 and over who consumed two units (a pint of beer or a glass of wine) per day showed brain changes equivalent to two years of aging.<<<


It made me think my brain will really be toast if I get COVID, or something like that. Come to think of it, or try to think about it, I'm not really sure, actually, what I was thinking. A man has to believe in something, I believe I'll have a beer.
Oh good. I just have to quit drinking at 50. Got a few good years ahead of me yet!
 
highfigh

highfigh

Seriously, I have no life.
I saw that. I also noticed the following study about the effects of even moderate alcohol consumption on the brain:

>>>Adults aged 50 and over who consumed two units (a pint of beer or a glass of wine) per day showed brain changes equivalent to two years of aging.<<<


It made me think my brain will really be toast if I get COVID, or something like that. Come to think of it, or try to think about it, I'm not really sure, actually, what I was thinking. A man has to believe in something, I believe I'll have a beer.
So, this is active drinkers who were infected with COVID? In that case, I'm safe- I stopped about ten years ago.
 
highfigh

highfigh

Seriously, I have no life.
That reminds me of the minute quantities of the carcinogenic nitrosamines in beer. Like you, I prefer to have a more relaxed life and I drink ¼ liter of wine almost daily rather than avoiding alcohol which is known to destroy brain cells.
Wait, wut? Wine doesn't have alcohol?
 
M

Mr._Clark

Audioholic Samurai
Here's the latest COVID risk levels map from globalepidemics.org. The number of new cases has continued to drop across most of the country. Hopefully we all get to green soon!

1646827649076.png
 
highfigh

highfigh

Seriously, I have no life.
Read my post again.
The one about drinking 1/4 liter of wine? I saw it- ever see the episode of Taxi where Jim Ignatowski was a straight-laced college student and had his first pot brownie? Don't be like Ignatowski.
 
Swerd

Swerd

Audioholic Warlord
Earlier today, I got another Covid-19 booster shot. My 2nd booster – a 4th dose. It was ½ the normal Moderna mRNA vaccine dose, so technically I've had 3½ doses ;).

I got both boosters thru my rheumatologist because I have an auto-immune disease. It's treatment suppresses my immune system. I hope its only partial suppression, and not complete suppression. So, just in case, I got the booster shots, last August and again today.

As of 23 Feb 2022, the CDC now recommends a 3rd booster dose of vaccine, for patients (those not moderately to severely immune-compromised), to complete their primary vaccination series. Patients can receive their Moderna or Pfizer booster (mixing or matching is OK) at least 5 months after completing the primary vaccine series. Patients who received J&J as their primary dose are eligible to receive their mRNA-type booster dose as soon as 2 months after the 1st dose.
 
Verdinut

Verdinut

Audioholic Spartan
Earlier today, I got another Covid-19 booster shot. My 2nd booster – a 4th dose. It was ½ the normal Moderna mRNA vaccine dose, so technically I've had 3½ doses ;).

I got both boosters thru my rheumatologist because I have an auto-immune disease. It's treatment suppresses my immune system. I hope its only partial suppression, and not complete suppression. So, just in case, I got the booster shots, last August and again today.

As of 23 Feb 2022, the CDC now recommends a 3rd booster dose of vaccine, for patients (those not moderately to severely immune-compromised), to complete their primary vaccination series. Patients can receive their Moderna or Pfizer booster (mixing or matching is OK) at least 5 months after completing the primary vaccine series. Patients who received J&J as their primary dose are eligible to receive their mRNA-type booster dose as soon as 2 months after the 1st dose.
My understanding is that the original dose of the Moderna vaccine contained 3 times as much of the mRNA portion as the Pfizer. Some people had more side effects with that stronger dose than what happened with the Pfizer. I believe the dose was later halved and that is the what you received as a 4th dose, and I received as a 3rd dose..

That would explain why some studies have shown that the Moderna now has a slightly superior protection, with 50% more of the mRNA potion.
 
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Swerd

Swerd

Audioholic Warlord
My understanding is that the original dose of the Moderna vaccine contained 3 times as much of the mRNA portion as the Pfizer. Some people had more side effects with that stronger dose than what happened with the Pfizer. I believe the dose was later halved and that is the what you received as a 4th dose, and I received as a 3rd dose..

That would explain why some studies have shown that the Moderna now has a slightly superior protection, with 50% more of the mRNA potion.
It's not as simple as the quantity of mRNA in the vaccine dose. The amount of total mRNA in the vaccine is less important than how long it lasts after injection.

Normal mRNA in cells has a wide range of stability, ranging from very short lived to lasting a long time. There are a variety of biological mechanisms that determine how stable – or unstable – the mRNA is. Understanding what these mechanisms are and how they work has been central to employing mRNA vaccinations. Without knowledge of these mechanisms, injected mRNA is very rapidly degraded, and not useful as a vaccine. Achieving greater stability was the main research & development effort, that over the past 20 years allowed mRNA vaccines to become a reality

Important differences exist between the Pfizer and Moderna vaccines that determine stability of their mRNA. Much of those details are complex molecular biology that the popular press generally avoids mentioning. Some of it is proprietary – carefully guarded trade secrets.
 
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D

Dude#1279435

Audioholic Spartan
I saw that. I also noticed the following study about the effects of even moderate alcohol consumption on the brain:

>>>Adults aged 50 and over who consumed two units (a pint of beer or a glass of wine) per day showed brain changes equivalent to two years of aging.<<<


It made me think my brain will really be toast if I get COVID, or something like that. Come to think of it, or try to think about it, I'm not really sure, actually, what I was thinking. A man has to believe in something, I believe I'll have a beer.
Keyword "per day". I must be in the "safe" category because I consume two beers 2-3 times per week.:)
 
Mikado463

Mikado463

Audioholic Spartan
I saw that. I also noticed the following study about the effects of even moderate alcohol consumption on the brain:

>>>Adults aged 50 and over who consumed two units (a pint of beer or a glass of wine) per day showed brain changes equivalent to two years of aging.<<<


It made me think my brain will really be toast if I get COVID, or something like that. Come to think of it, or try to think about it, I'm not really sure, actually, what I was thinking. A man has to believe in something, I believe I'll have a beer.
Like Mark Twain, I drink only in moderation, one Manhattan at a time ….
 
mtrycrafts

mtrycrafts

Seriously, I have no life.
Keyword "per day". I must be in the "safe" category because I consume two beers 2-3 times per week.:)
So, if it is every other day, will that increase the age by how much? :D
Probably best to stop altogether and brain will never age?:D
 
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