I can honestly say there is a difference. I've hooked up my Denon x4000h to not only my old Polk RTi A9 speakers, but to my new Focal Electras. It sounded great don't get me wrong. I have an older Denon that I still use for my 5.1 setp. But I had a 30 day trial on the x4000h so I figured I'd do a rock solid compare and contrast. I'm not a placebo effect kinda guy, I just upgraded my speaker wires to BJC for example and hardly noticed anything whatsoever. But the difference between running the AVR and the Anthem or the McIntosh on both sets of speakers, literally no contest. I know there are a lot of die-hard AVR guys on here that this might piss off, but I am just speaking the truth and what my experiences are. The Denon made them sound flatter, less punchy, and with lesser clarity. It's almost as if there was a sheet over the speakers. The lows ESPECIALLY were less pronounced, didn't have nearly the same punch and crispness, and even in the mid to high range with instrumental sharpness and vocal purity, there was a massive improvement in how the 2 performed. The Denon ran hotter, it didn't keep the same clarity when I cranked it really loud, and overall just seemed like I was overworking it, more distortion at high volumes, which is a tangible spec you can compare, just overall more detailed sounding music all the way through the band. I also had no use for the 7.1 even the video I'd never use, so why have all that spliced up to the power supply? All these cool extra features jammed in that just clutter up the electronic noise inside and complexity of it that I wouldn't use anyway. I have no other way of slicing it. The music sounded better. Not by a little, by a lot. More than any other upgrade you can do, save speakers.
Had the Denon been on the same page as the Anthem, you bet your ass I would have returned the $5500 Anthem and kept my $700 Denon. I'd love to pocket almost $5k for music, dinners, hookers, etc. But I ended up returning the Denon. There is a difference, and I have zero regrets. If you guys don't believe me, that's ok. I am giving my truthful experience, and when I had friends over, one being an Audioholic himself with a more expensive setup than me, he noticed a difference too. No contest.
Since i know this is one of the most heated discussions on here, I am leaving it at that. Figured I needed to chime in my 2 cents.