What remote are you using? Please post a photo- it matters.
Use the OEM remote and set it to Zone 2 with an unused source and look at the volume setting- if it's too low, raise it but if it's close to maximum, use the volume control to reduce the setting to -30dB if you're using that scale- if you're using the other, set it to about 20. Then, switch to a source that you DO use and see if it works.
Regardless of whether it works or not, go into the Audio section of the menu and set the volume limit to -15dB for both zones- it will save your speakers at some point.
BTW- if you use the OEM remote- DO NOT press the numeric button that corresponds to the number 1- I did that accidentally when setting up a, AVR-3310CI and the volume went to WOT.
If this doesn't work:
Turn the AVR on, select Tuner and find a station for the main zone. Then, turn on Zone 2 and select Tuner- if it doesn't play, check the menu and find out if the amplifier assignment changed. If it has, change it back to what you want. If it hasn't check the Zone 2 line out to find out if that's working.
Just because it can help, find the IP address for each AVR, use the GUI and check the assignments- if something isn't set the way it should be, change it. The GUI has a 'Save' button and you can do this for both, separately.
DO NOT use WiFi for saving or loading the configuration!
Once you have saved the configuration, do a hard reset, then look in the menu for the IP address. If it's not connected, do that so you see a good address, then use your computer's browser to log into the AVR again so you can load the configuration.