The Dina Ellie scene is different in the game. They combined two semi-related occurrences into one in the show, the kiss discussion and the immunity issue. One aspect is better in the game and one is better in the show. In the game, Ellie tells her she is immune during the kiss discussion and Dina thinks she is joking. Then she finds out first hand and the second interaction happens. In the show though, they had the confrontation about it, which I liked better.
Unless they change it, there is Seattle Day 1, 2 and 3 with Ellie. Then the other side, Seattle Day 1, 2 and 3 with Abby and the WLF. So there should be plenty of WLF and Seraphites, with some flashbacks mixed in. From the previews, it looks really well done. I like that they gave some background on Issac, Wright's character, because you don't know much about him in the game except that he's their leader. Wright also plays Issac in the game!!
There look like there are two aspects that may also have changed though: Seattle isn't totally flooded, and how the Seraphites get around Seattle without detection in the game. There are two big sequences that rely on these things.
I KNOW where this season will end lol, and if they pull it off, it will be pretty nuts. The E5 preview looks to be setting that up.
Druckmann is the director of the game and the show, without him, the show would not be good because he understands what the story is trying to say. Look at Uncharted the movie vs. the games. Uncharted is one of the best game series ever done and the movie they created from it was absolute GARBAGE, because it slightly left out the core point of the story that made it good.