Rickster is pretty much on. The app I'm running is the Crestron App from the Apple App store and it's being shown on my Verizon phone. I have it on my iPad as well
I'm not sure how products like iRule and others really handle whole house audio integration, but leveraged with Crestron it allows for my entire home to not just be controlled, but maintained with the same high level of reliability and simplicity. Pick a room, pick a source, everything turns on, switches, and works automatically. So, I'm not switching between sources, I'm not having long macros repeat themselves, it's non-directional, etc. It just works.
I don't like it anywhere near as much as I like using the MX-850 remotes I have everywhere which are tied to rooms directly, but when I'm looking at XM stations or walking the house setting things up for a party, it's a great way to handle things. Also nice when I'm already streaming things through AppleTV.