I couldn't see having two system in one room (so I have five systems in five rooms

). Most of mine are based on a multich setup using an avr as central unit (still use one older setup of just 2ch stuff, tho). If you like the 601s best, I'd simply make them the L/R speakers. Do you have a sub?
As to which avr (audio video receiver) I'd use, the one that does the most for what I need.