I just spent the last few hours with my new Harmony 300 remote. Work, (HHGREGG) had them on clearance for $14.95.
I love it! I wish I would have spent a little more and got the 650, but for my needs, the 300 does everything I want. Very easy to set up. The drag and drop feature was a breeze.
I'm going to re read this thread, because I too am wanting to set the volume so I don't have to toggle between device buttons.