I both agree and disagree with this statement.
While I had a simple 2.1 system in my office for a while, and it did sound quite good (not great speakers, but good mains) I will say I do enjoy it more now that it is 5.1 simply because dialog is much better with the center speaker in place.
My surrounds barely have a job in that room, but they do it well.
Another thing I noticed when selling speakers is that there was a system we had set up as a demo that sounded pretty great for movies. It's really all we ever used the demo room for. Loud, bombastic movies. It was the lowest end Klipsch (synergy) series at the time and they were big speakers that could play loud and handle the large dynamic changes in movies well.
They were horrific for music. I was shocked when we played a music demo we used on our 2ch demo rigs. I couldn't believe speakers that were so good at large dynamic changes in moves, had clear dialog, were absolutely horrifying to listen to any music on. Turns out they were good at higher frequencies and a bit of mid range, but totally died in the lower range. Clearly a very bad design on the large towers. The center and surrounds were fine, but I've never thought 2 VERY small speakers with a sub sounded all that great. I'm sure some do, but I just haven't heard them.
So what all that means is that yes, a GOOD 2ch system will sound leaps and bounds better than a surround setup that is "fine". However, I say it greatly depends on what the system is for. If someone were to ONLY listen to movies and TV, it's entirely possible that their system will sound good for movies and TV, but be horrible for music. Counter intuitive, but I've witnessed it.
Granted, all this was before I got to hear really good speakers in person and WAY before I ever owned any so if I were to hear such a system now I may think it sounds horrible for everything. Sonic memory isn't all that good from what I hear (ba dum tss).