That room is over 10K cubic feet, assuming it's not open to any other rooms/hallways/etc; 2 subs should be a
minimum, or have them nearfield.
If you can wait another 4-6 weeks, Audioholics should have reviews of the VTF-15H and FV15HP; the PB12-Plus review went up tonight (which is actually $200 more than you listed.) They're also reviewing the Aperion speakers you're asking about, so maybe you should sit tight on your wallet for the moment and see what they have to say.
What about bookshelf speakers up front? Since your weighted more towards TV/movies than music in a huge room, I'd spend more of my budget on the subs - I don't see what having towers up front will do for you...
