Well, my dream setup starts at $40K for the speakers only, so I won't explore that here...
If I had a spare $10K lying around to set up a completely new (2 channel, no physical media) system it would be...
Anthem STR integrated
Bluesound Node 2i streamer
KEF R11 speakers
(2) Hsu ULS-15 MK2 subwoofers
That comes in a tic over $10K if we go by MSRP... I've listened extensively to the KEF/Anthem combo and it is really, really, really nice. The Bluesound to get my streaming kicks and a couple Hsu's to fill in the bottom octave nicely. Yeah, I could live with this one.