A drop of water coming down on concrete at a constant interval of time will make a hole in the concrete.
A speaker installed on a subwoofer, no matter how well it is anchored, will be shaken internally by the sub's vibration and internal parts will be affected in a period of time associated with the rate of use and intensity of use of the subwoofer.
You may get away with this for a month, a year but in time, you will have, I firmly believe, a failure.