Probably. Same with the Fire TV stick IIRC. IMO, most of those types of devices use some sort of BT. The full Fire TV box does too, I believe. The Harmony website has a compatibility tool on the page for specific brands and models. https://support.myharmony.com/en-us/compatibility?utm_source=logitech.com&utm_medium=support search&utm_campaign=harmony support The compatibility tool shows that the Fire Stick is controlled by the Harmony Hub.
