I you have not used MDF before, you should know that you must use a countersink before you screw your peices together, otherwise the screw heads will not be flush and when you try to screw them in further the threads will strip your hole.
Test your crossover before yo seal it up in the box.
If you are willing to spend a few more bucks, I would also install your speakers using tee-nuts and machine screws, that way if you ever need to replace the driver or get to the crossover you dont have to worry about The MDF falling apart from putting screws in and out to many times.