You may be asking for an apples to oranges comparison.
They both use the same speakers but one has two identical mid/bass drivers.
One of the mid/bass drivers is used as a mid/bass driver and the second has it's range restricted to only the bass.
Alll else being equal and the design is applied correctly, the 2.5 would have a bit better bass.
Of course, if the speakers aren't the same in both, no realistic comparison is possible. Likewise, one cannot say if one particular 2 way is better than another 2.5 way system, or vice versa.