Since it's a plasma, you need to let it break in for the first 100 or so hours, so that means don't turn the brightness or contrast up too much and make sure there are no static images left on the screen for too long. Burn in shouldn't be a problem on modern plasmas, but you can still get some image retention for a while, and that may scare you if you get it. Just start your calibration wiht avia or dve and since you spent that much on your tv, you may want to spend another couple hundred to have it profesionally calibrated after it's broken in. Check around on avsforum for some reccomended settings as I'm sure many have gotten that tv dialed in pretty good and their settings will be a good place to start, but may not be the ideal settings for your tv since every set is different.