I never try doing a 45° miter cut on MDF. The thin edges crumble. It's hard for me even with good plywood like baltic birch.
Mentioning how MDF and plywood come in metric thicknesses reminds me that I hate how this creates problems when using our non-metric tools. Speaker building is a good example, because nearly all drivers are made in metric dimensions. Figuring out how large a hole to cut for a driver 148 mm in diameter while using non-metric cutting and measuring tools is a mighty pain!!
And don't even mention that we measure length in inches (which by itself is alright) and fractions of inches (halves, quarters, eighths, sixteenths, etc.) which are awful to add, subtract, or divide in your head. If we even used inches and decimal inches it would be a lot easier than those dreadful fractions. If you have a board 7 and 5/8" wide, quickly (without using a calculator or pen & paper) tell me how far from the edge is the center. The answer is 3½ plus 5/16 = 3 and 13/16"). If we used centimeters, half of 19.4 cm is 9.7 cm. That's much easier to do in your head.
It's funny that we still call non-metric as the English system because the British abandoned it for metric a long time ago. And that brings me to my last point in this rant… if we had changed over to the metric system back in the early 1980s, as planned, none of this would matter today.