This is true.
As a practical matter, very few cases have been decided based on the 10th Amendment. This is a pretty decent summary:
>>>The 10th Amendment . . . is generally considered to be nothing more than a stamp of approval on the system of government set up by the other provisions of the Constitution. However, it does stand for one particular principle: that
the federal government . . . can’t force a state to use its own resources to comply with a federal regulation, statute, or program.The quintessential modern cases that illustrate this idea are
New York v. United States (1992) and
Printz v. United States (1997). In
New York, the Court reviewed a Congressional program that used several different approaches to realize the goal of New York State complying with federal standards for radioactive waste. The Court held that . . . forcing N.Y. to take N.J.’s radioactive waste if certain deadlines were not met, was unconstitutional. This was so drastic a step that it was essentially the federal government compelling a state to comply with a federal mandate.<<<
The Tenth Amendment, written into the Constitution with the other amendments of the Bill of Rights
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