Yes, you make no mention of what kind of speakers you are using or their size, or the subwoofer. Bookshelf? Floor standing? If you got big honking 12" or 15" woofers in some big old studio monitors but you have a small sub with a 10" woofer, you may not be getting much added benefit from having a sub.
If you are using bookshelf or smaller front speakers, either way it would be best to set them to "small" on your receiver, and play with the crossover frequency controls on the sub to see what works best.