I set my speakers up as monitors (set to small, XO 80 Hz) and SX-1010 as LFE. I run Audyssey for speakers and subs. Then I use Audyssey Bypass L/R + Dynamic EQ.
So I actually BYPASS Audyssey. But I use DEQ. If I could have just Sub EQ + DEQ without Audyssey altogether, I would do it.
Assuming I get five SX-T2 towers, I would still do the same. The 5 top cabinets (treble & midrange/ SX-T1) are set to Small. The bottom 5 cabinets (bass/ SX-1010) are LFE. That means a total of 10 channels of amps.
I like this better than 5 full range towers configuration because I get 5 subwoofers around the room.
So in effect, I'm really doing 5 monitors + 5 subs. But aesthetically, they just look like 5 full range towers and zero subwoofers.