Pro audio is very competitive and higher power is needed as compared to home audio. In addition, the chassis on home audio amps is often expensive machined aluminum parts to look pretty, where as the pro amps use plain sheet metal that is simply painted.
I personally used to use only home 'high end' amplifiers, pre-amps, etc. I used to use all McIntosh amplifiers in my main system. Today I use pro audio amplifiers in all of my systems along with other pro audio gear such as pro DSP xovers.
There are few pro amps with consumer RCA inputs. One example is the QSC GX series intended for DJs. I would, however, recommend using a consumer to pro level voltage converter and using an amp like the Yamaha PxxxxS series, as these do not have fan noise to deal with, and are superbly engineered amplifiers. Instead of a converter, if you want a very high performance/serious 2 channel system, you could use a Behringer DCX2496, which has suitable internal pre-amps to boost the consumer line to pro level voltages. In addition, the DCX unit allows for extensive control of your speakers and provides for advanced crossover abilities to seamlessly integrate speakers with subwoofer(s). You can even use a DCX to control fully active speakers (no passive crossovers). I use a DCX in both of my systems, which are both fully active.
-Chris