The indoor can be wired easily, especially 2 of them. The other two indoor speakers would be more difficult. Outdoor speakers would be a very big pain but if the quality/price would make up the difference I might run wire anyways. they would be about 50 feet away on the outside of a metal building though.
Something that is important is having the indoor on one channel and the outdoor on another. Both channels need to be able to play simultaneously or one at a time.