I think this is if you are goin to use the active cancelling Eq. In that case the subs need to be at two heights at least. As far as I'm concerned if this is going to happen then it will require custom construction. This will pretty much have to involve in wall subs. You could easily use the TL design I have on my in wall system and have a number at both ends of the room, and the wall space would only be slightly deeper than normal. If anyone wants to experiment, I can send the plans, or even get them made up. The dimensions are in the C & C machine. I have to say that sub is a very good performer indeed and lacking in coloration. I think they would really fit the bill for this. They don't need huge amps, and the 10" driver is adequate.
But what I found interesting is that using full range speakers may well have an advantage. In addition the TLs at the end of the room have their outputs at the top. The output from the shorter lines of the left and right mains, are between the bass drivers and the long lines ports. In addition the ports from TLs cover a wider frequency range than reflex ports. So it gave me insight as to the very natural and even bass response of the rig. It certainly is the most natural reproduced bass I have ever heard, and by a big margin. As I said I think a lot of this was dumb luck. But I have been puzzled why the bass is of the quality it is. It was well beyond anything I expected.