All components work in synergy, because they are working together. If the question is whether the separate components are synergistic, thereby working in synergy to produce synergism (the total effect being greater than the sum of the individual components), that would be another question - one that I am ill suited to answer.
I will tell you that after visiting too many stereo shops, and auditioning, possibly, 100 speakers, I find PSB and NAD to be a rewarding combination to my ears. I don't own either right now because I'm trying new stuff, but I seem to be drawn to that sound. So, maybe the synergism is three way - speakers, electronics, and my ears.
John