If you have the best of everything else then you may hear the difference. There are other factors that contribute more to sound quality than the pre-amp. For example, the quality of the recording, the player, the loudspeakers, the room acoustics, and the power amplifier. If you compare the specifications of each components in the chain in terms of just frequency response, dynamic range and total harmonic distortions, you can already see that the preamp is the least of your concern. It functions very much like a power amp but it deals with much lower level of signals.
Room acoustics and loudspeakers are two important factors. If you compare two different brands of speakers at the same price point (say $1,000) you will hear the difference immediately, but you may have much more difficult time hearing the difference between a $1,000 preamp and a Denon AVR3808. I tried it and found that it was a waste of time. Some day I would like to try out a higher end preamp such as a McIntosh or Classe, if and when I manage to get a pair of something like the B&W 802D just to make sure the speaker has high enough resolution to begin with.