Quite a bit
The Muro's go 12Hz lower, from 50Hz to 38Hz (no doubt due to the 8" woofer over the 6.5"), have a higher spl rating which means they'll play louder, and go 2kHz higher (out of our hearing range if it makes a difference). They are also 3 way opposed to 2 way, so the midrange is much improved. Finally, the tweeter is directional - a big plus with mounted drivers. Not much of a fair comparison IMO.