That "±3 dB" thing means that, when fed with a signal of a certain voltage within the 50 Hz to 20 kHz range, the speaker will give you an audible sound that's no more than 3 decibels louder or softer than the speaker's median response. If a speaker actually plays within ±3 dB through its entire useful range, that's good. (And ±2 dB is great.)
There are a couple of problems with this spec, though. First of all, two speakers with exactly the same rated frequency response can sound completely different. Say one measures +3 dB from 80 Hz to 500 Hz, and -3 dB from 5 kHz to 20 kHz. It'll sound very bloated, boomy and dull. Another speaker might measure -3 dB from 80 Hz to 500 Hz, and +3 dB from 5 kHz to 20 kHz. This one will sound very bright, thin and fatiguing. Same specs, completely different sound.