Hey there, Daniel. Welcome to the forum.
The high-level inputs are for feeding speaker wire (say, for one of the front speakers) to the sub, and then you'd run more speaker wire from the sub to the front speaker. The low-level inputs are for use with a subwoofer output on a receiver, and those are the way to go almost all of the time. The high-level inputs don't allow you to do bass management (letting the receiver decide which speakers should have the low frequencies sent to them), but the low-level inputs do allow that.
You'd want to get a receiver with a subwoofer output, and just about every (if not every) receiver that you'd get for surround sound will have one of those. To run two subs, you'd just use a y-splitter to split the subwoofer output signal from the receiver into two lines, and then you'd run one of those lines to each of your subs.
Does that answer your questions?
Adam