Bookshelf vs. floorstander
First, the M22tis have two woofers and a single tweeter, it is a two way bookshelf speaker. In comparision, the M60s have 1 tweeter, 1 mid driver, and 2 woofers. This 3-way design allows for a more refined mid range. The additional drivers and higher power handeling of a floorstander allow it to achieve higher SPLs. Finally, they can be crossed over with the sub at a lower frequencey, or you can set them as LARGE to have the mains and sub produce LFE.
Since your room is fairly small and you don't do any two channel listening, I think the bookshelf speakers will work well.