Move the amp. Is this when a cable is connected, or not? If it is with the cable, you need to realize that without being terminated, it's acting as an antenna. If it doesn't matter whether the cable is connected, move the amp and look for power/accessory wiring near its location.
Is this actually hum, or it it buzzing and whine that increases/decreases in pitch with engine RPM? What power source is being used- inverter, batteries, plugged into AC power?
Lay out the system and post it here.