You can put a sub anywhere and it will work.
But, if you want the BEST sound, you may need to move it around a bit. Those who care most about audio, above all aesthetics, will move that sucker into the middle of the room if they need to for the best audio.
But, usually it is a compromise between good sound and great sound combined with the room the speaker is in. No sub will just work perfectly wherever it is, whichever room you put it in. That's just crazy talk.