I agree with Shady on the suggestion of using that kind of driver as mid-range speaker in a three-way system, with a subwoofer used as a woofer. I would also suggest an Air Motion Ribbon tweeter such as the Airborne RT-4001 which a very smooth frequency response:
https://solen.ca/wp-content/uploads/rt4001.pdf
Of course, the possibility would exist if their relative efficiency is close. That could be an excellent match.
The advantage in a 3-way system, is that you can divide the frequencies outside of the critical range of 300 to 3000 Hz. For instance, my three front cabinets contain 3-way systems which consist of the above mentioned tweeter, two Peerless P830991 5¼" Mid-woofers and a Dayton RSS390HF-4 sub. The filter frequencies are 190 Hz and 3500 Hz. Those speakers are amazing and I just have to eventually EQ them mainly for the low frequencies because of room interaction.
If the Markaudio full-range driver has a relatively smooth response between 300Hz and 4KHz, a close sensitivity to that of the RT-4001, then you would be all set to proceed with a very decent 3-way system. The Airborne tweeter has an efficiency of around 94dB. If possible with the response of this Alpair speaker, I would crossover at between 3200 and 3500 Hz to the tweeter, and at around 250-275 Hz Hz to a good sub, one Dayton RSS210HF-4 for instance. This is an 8" subwoofer. If you decide on this sub, I could figure out for you a decent BR cabinet size for it. Both the tweeter and the mid-range driver could be installed in a closed box within the subwoofer cabinet.
IMO, the 3-way system is the best compromise for a good loudspeaker system. Each transducer operates in its best frequency range, with less possibility of dispersion problems, less cone breakup possibility, less intermodulation distortion and higher power handling as well.
That is what I consider a valid suggestion.