Most likely no, that won't work. The box, amp, eq'ing and driver are all carefully selected and modeled to work together. It's not as simple as it seems. I know with regular speakers it's pretty much guaranteed to not turn out well. Did you try contacting the manufacturer to see what they recommend? If you could find the T/S parameters of the speaker we might be able to find a match. You should be able to get that info from Klipsch.
*Edit: Pics are always good too!