No. Bi-wiring only makes a difference in your wallet, or if you imagine things and you think you hear a difference. Don't worry about how to hook it up.
You can use either post, but make sure that bridge is still connected. You can also Bi-amp them with 2 sets of wires from 2 outputs (has to be a front output, and the same signal).
If break in makes a difference, which many don't think it does, its in the bass driver. Its only mechanical though, and it doesn't take very long, maybe a couple hours. Thats IF it does. Playing the speaker is the only way to break it in.
I personally think that the speakers don't change, but you do. You get used to the sound, and then start to like it(unless its utterly horrible).
Hope this helps.
Edit: Beat you J
SheepStar