I assume optical audio is for getting audio out of the TV and back to the receiver. In my experience, with video up to 1080p, this is a non-issue if you use any decent quality cable. Decent doesn't mean expensive. Read Amazon reviews and buy accordingly.
Once you get to 4K, the entire world seems to be hit or miss. Some work great, others not at all. So, if this is part of a 'permaently fixed' installation, then you MUST run conduit so you can replace the cable fairly easily. No conduit = bad choice! 4K 18Gb/s HDMI is best achieved with fiber optical HDMI. It's expensive, but reports are that it is worth it for reliability. More and more 50' 4K 18Gbs cables are popping up regularly