I'd certainly go along with alandamp, in saying that the rear speakers should be placed directly behind the listener, with less separation between them than the front left and right speakers.
You should listen to the tone tones from each speaker and ensure that they all sound roughly equal in volume. Most of the time the surround channels just add ambience, and you shouldn't turn their volume up so they become distracting. If you want a good DVD for trying out your surround speakers, I suggest Star Wars episode II. The surround effects on this DVD are the best I've heard.
THX favour surround dipole speakers (more diffuse sound than ordinary speakers), the argument being that the surround speakers shouldn't make you want to turn your head around when watching a movie, because there isn't 360 degrees of picture.
The lack of symmetry in your room will make the sound placement much worse (positional effects, panning, etc.), because each speaker is in its own acoustic environment, esp. the surround left and right, because the right is not near a side wall, unlike the left. The symmetry where you are seating is also important. It's better if you can have as much symmetry as possible, as this will help speaker imaging.