A small lesson in physics is called for here.
The key to good sound is efficiently moving the air in the room. That's done by the cones of the drivers moving back and forth. The larger the surface area of the driver, the less it has to move. Also, a small speaker can only move so much. This forces you to accept the laws of physics which state that a small speaker will have difficulty moving sufficient air in a large space.
While small speakers are fine in a small room, they can easily be over-driven when asked to fill a large area with sound.
IOW, those Nanostats, or other similarly sized speakers, are fine when used within their design limits in a smaller environment, but asking them to fill a room that sizes like asking a Fiat 500 to tow an 8,000 trailer. It might do it for a period of time, but it ain't gonna be clean.
Now, I know what you're thinking: A sub-woofer can do the hard stuff, right? Well, only up to a point. They only go up the frequency range just so far and at some point the satellites have to handle the rest of the load. That means the satellites have to go low enough to meet (and overlap) where the sub starts to drop off.
So, you might want to consider some somewhat larger speakers.
And now back to our regularly scheduled programming...