Thanks for the responses.
So many of the subs now have DSP (Emotiva, SVS, for example) and there is no mention in reviews etc. about latency issues. While Audyssey matches any latency issues, these subs are presumably designed for use in an system that does not involve Audyssey (or equivalent).
I am just thinking out loud here, so please feel free to correct or dispute if you believe (or know) differently:
I suspect the 1-2 ft. at the speed of sound is probably challenging the limits of human perception (especially in these low frequencies, while the harmonics of the impact is still carried by the higher frequencies so will be in time with the main music).
I do have a specific application I am considering. It is using old school analog system with a SVS AS-EQ1 to EQ bass (the AS-EQ1 is Audyssey MultiEQ XT32 for subs only). I called SVS about this type of set up. The Tech Support rep said locating the subs 8 ft closer than the mains would compensate for it, but he was actually running that same type of set-up with the subs positioned next to the mains and hadn't noticed any difference. I'm sure he was telling the truth, but I also think it is reasonably likely that he might notice a difference if he had a corrected setup to A/B against.
For my case, I do not think I'll have trouble locating the subs 8 ft closer (though that might not allow for ideal sub placement).