Hell yeah. Search around in these forums enough and you will find people who like the sound a particular brand makes, and they'd be right!
There are people who prefer the Klipsch sound, and those who do know what that means. I prefer the Def Tech sound over many other brands, but I also don't like Def Tech subs. Subs though, in my opinion, are more objective in selecting than other speakers. I like the sound that Aperions make (the ones I've heard) I don't like the sound that Polks or JBLs make for a couple examples. And I hate the sound that Bose makes, muahahahaha had to throw that in there.
It's really all about what sounds right to you, and you may even figure out that your fronts NOT being timbre matched is what does it for you acoustically! I found out the hard way it didn't do it for me.