Welcome to AH. I believe the main gripes you will find with Bose here:
Speaking from personal experience they are way too expensive for the quality they put out and their bass (subwoofer) output is absolutely a joke across their entire line up. Doesn't even matter if it is their $4k system.
You need a receiver that can do two zones. 5.1 in the house and 2.0 outside. What kind of run length are you talking about for the outside?
Are you doing any critical listening? Music/HT percentages? volume of inside space the 5.1 will be setup for?
Run length, I assume, means listening area? The deck is probably about 60' long, with the main listening area on the side of the pool nearest the house and in the pool. I can either mount two speakers on the deck coming off the upstairs or get some landscape types to sit on the deck.
I've had the Bose Acoustimass system before, but it was the 400 series, IIRC (one small base module and two sat). I also bought it in the mid-early 90's, and wasn't terribly impressed with the base, but in a Navy barracks room, it was plenty.
I'd really like to replace the Cerwin Vega's simply because they are furniture. They sound fantastic, especially for my type of music (Metallica, GnR, etc), but I just don't jam like I used to. The system will be mainly used for watching TV.
If I DID plan to go with the Bose, I'd certainly get the factory renewed ones. I bought a JVC professional VCR like that and it was just like buying a new one at half price.
Edit: As for the upstairs space, not sure yet. We're waiting forever and a day to close on this house. Going on 6 weeks now.
MORE: I have also had the Bose 301 speakers, again, early 90's. The sound was crisp and sharp, but as you mentioned, not a lot in the way of bass.