I believe there is a difference in wires. The problem is, for me, I can't hear the difference. However, there was a time that I thought I could and I read hundreds of opinions concerning different types of wires and their affect on the sound produced. What I noticed was, although there were differences, the vast majority heard the same characteristics from similar wires. The evidence seemed to suggest that if you listen and study enough, (and can afford to) and your ears are good enough, the wires can make a difference in how you hear the sounds.
I don't have the patience for that kind of study and I certainly don't have the ear to hear the difference. So, I'll blissfully enjoy my low/mid-fi experience. Bring on the music.
John