I wouldn't say better or worse with that information, but closing it off is a plus. I would say treatments would be a benefit for sure, but choose the sub, get it in and then you will probably want to pick up a SPL meter so you can run some numbers on it. Then you can determine how good or bad response in your particular room is and decide if treatments and/or EQ can solve the issues. The reason a square and near square rooms are not good for bass is becase of the wavelengths of bass frequencies in the bottom octave - they will reflect and overlap (standing waves) and potentially cancel out at particular frequencies because they cross at perfect angles. You can't move the walls, but you can adjust how the waves behave in the room with treatments. I have also seen others adjust the dimensions of the room with a false wall (basement, dedicated HT room, etc...), though it doesn't sound like that would be a viable option in this room.
I heard the VTF-3 Mk2 in a room that was about 18x14x8 and it had no problem delivering adequate bass.