If you have a digital TV, the signal through HDMI and the signal chain stays digital and in most cases will be coming from a digital source, so there is no signal processing between digital and analog signals. Not sure about measure differences but there must be with sensitive test gear
But, it can be tricky at times with the hand shake issues that you don't have with component video. How long of a video run are you talking about?
Maybe, that will be part two of another DBT process