I was originally going with bookshelves, but given the size of my room and my seating position (12 ft from speaker location), I may have to go large. the room is 16x16, with a 12 ft vaulted ceiling. It opens up into a similarly sized kitchen, except the kitchens ceiling only goes up 11 ft at the highest point. So, it's a decent size space to fill. I think the Ascends wouldn't have a problem filling it. i don't consider the 340se's a bookshelf, more like a mini-tower really when you look at performance. I spoke with a rep from Axiom and he said the m22's would sound a little thin in the mid-base region and reccomended at least getting th m50's with that space. Personally, I don't think the m 50's give enough of an improvement to be worth it, so might as well go with the m-60's which would be a significant improvement over the m22's. As you can see, I've gotten upgrade-itis before i've even purchased anything. it is contagious, or so I've been told.