I’ve worked on similar home theater setups and queries while working as an AV system integrator. As a result, I have experience with various speaker configurations.
For your Onkyo RZ50, it should handle 4-ohm speakers like the Arendal 1961 Monitors. But ensure you set the receiver to accommodate lower impedance. The RZ50 offers around 120 watts per channel at 8 ohms. Thus, it can deliver more power to 4-ohm loads, potentially around 180 watts per channel.
The ASCILAB C6B is famous for impressive clarity and dynamic range. Hence, it is a solid choice for your room size (11’ x 17’). You must ensure that they are correctly positioned. The ideal distance will be 1-2 feet from walls. This distance will provide the least boundary interference and the most bass response.
For your sub, the SVS 20-39PC-Plus pairs well with either speaker option, providing robust low-end support. You must keep a mental note of the room’s acoustics. You can do acoustic treatments in the room to improve sound quality.
In short, both speaker options are excellent. At the end, it may come down to personal preference in sound signature.