Covid Booster Shot

[davidscott]

Anyone get one yet? I got my 3rd Moderna shot Tuesday and I felt pretty miserable Wednesday. Sore arm body aches and a headache with chills and fever off and on. Now Thursday nothing so it was worth it. I'm thinking this might be like a Flu shot in the future where you might need one every year.

 

[ryanosaur]

I'm not eligible until mid-Nov. I will, and will likely seek out a Moderna bosster for my Pfizer mains.

I just had a sore shoulder with my primary Pfizer shots. My understanding is that the Moderna has more of the active mrna agent in it.
It would suck being wiped out by the booster... I'm one of those people that have experienced vaccination illness in the past. Hate it. Always got sick after a flu shot. Seriously got destroyed by the Hep A/B vaccine... series of 3 shots, sick for almost a week after each one!
*shrugs

 

[Hetfield]

I'm not eligible and I don't think I will be at any point but would. My mom should be but haven't heard anything, 75 and diabetic so I'm sure she is. She got Moderna so I guess Pfizer did be best.

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[Swerd]

I got my booster shot late last August. I have an auto-immune disease and I take meds that partially suppress my own immune system, so it can't attack me. My rheumatologist was giving out boosters starting back then. All 3 of my doses were Moderna. I had similar arm soreness and general aches and pains for about 1-2 days after the shot, similar to what I had last March with the first 2 doses. These flu-like symptoms (aches, pains, general malaise, and fever) are signs that your immune system is responding to vaccination. You should expect them. I'd worry if I didn't feel that way after a vaccination.

@Hetfield If your mom is 75 and diabetic, she is definitely eligible for a booster. Get after her to get it done.

 

[Hetfield]

I got my booster shot late last August. I have an auto-immune disease and I take meds that partially suppress my own immune system, so it can't attack me. My rheumatologist was giving out boosters starting back then. All 3 of my doses were Moderna. I had similar arm soreness and general aches and pains for about 1-2 days after the shot, similar to what I had last March with the first 2 doses. These flu-like symptoms (aches, pains, general malaise, and fever) are signs that your immune system is responding to vaccination. You should expect them. I'd worry if I didn't feel that way after a vaccination.

@Hetfield If your mom is 75 and diabetic, she is definitely eligible for a booster. Get after her to get it done.

Definitely will, she is not against it, she just hasn't heard anything. For the vaccine itself her town set up everything. I guess she was waiting for the same thing.

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[mtrycrafts]

Had mine Oct 5.

Definitely will, she is not against it, she just hasn't heard anything. For the vaccine itself her town set up everything. I guess she was waiting for the same thing.

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Just check out one of the larger drugstore like CVS or Walmart. Walked in, one or two in front of me, filled the paperwork(always the paperwork) and when there were more than a couple so vial is not wasted, got it.

 

[Hetfield]

Had mine Oct 5.


Just check out one of the larger drugstore like CVS or Walmart. Walked in, one or two in front of me, filled the paperwork(always the paperwork) and when there were more than a couple so vial is not wasted, got it.

Does she have to bring her original vaccine card?

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[Bernie Williams]

Walk in basis at walmart in San Antonio. They will fill out your original vaccine card with another entry just like the first two. I had almost no reaction to the first two shots, third one smacked me down for a couple of days, flu like symptoms.

 

[Hetfield]

Walk in basis at walmart in San Antonio. They will fill out your original vaccine card with another entry just like the first two. I had almost no reaction to the first two shots, third one smacked me down for a couple of days, flu like symptoms.

Oh boy I wonder why that seems to be the case? Did you mix vaccine shots between original and booster?

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[cpp]

Got my 3rd Pfizer Sept 9th. No issues at all..

 

[Bernie Williams]

Nope, all three were pfizer. My daughter and her fiancé both got breakthrough covid (both vaccinated). Both sick for several days, probably worse then my little reaction. I would not want to get COVID and be unvaccinated at my age.

 

[ryanosaur]

Oh boy I wonder why that seems to be the case? Did you mix vaccine shots between original and booster?

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Everybody reacts differently, and it changes... I know people that were fine after the first but socked after the second... and the other way. I just had a sore shoulder after both of mine.

 

[Hetfield]

Everybody reacts differently, and it changes... I know people that were fine after the first but socked after the second... and the other way. I just had a sore shoulder after both of mine.

I didn't get anything for either except for a sore arm. Really was absolutely nothing. Oh ya know what's funny is I get a a worse reaction from the flu shot. That kinda messes me up for 12 hours or so.

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[mtrycrafts]

Does she have to bring her original vaccine card?

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Yes. I think think that way the county health will be notified, and the state so you can get a state vax id updated eventually.
Make sure her doctor also is told so it gets into her med record.

I went home for it and perhaps did the same or next day.
Actually I meant to say Walgreen but Walmart has it as well.
The original two shots were at the local hospital, a well organized sign up and event but not anymore, you are on your own that is just as easy now.

 

[mtrycrafts]

Nope, all three were pfizer. My daughter and her fiancé both got breakthrough covid (both vaccinated). Both sick for several days, probably worse then my little reaction. I would not want to get COVID and be unvaccinated at my age.

Well, you don't want it at any age, even if one is not hospitalized at all.

 

[lovinthehd]

Not sure what our local plans, if any, are for a booster...haven't seen any announcements like we got for the initial free shots.

 

[Mr._Clark]

My understanding is that the Moderna has more of the active mrna agent in it.

This made me curious about the boosters, so I googled it. I believe you are correct:

>>>If you had Moderna for your first two shots, Poland says, you might consider getting the Pfizer booster because it's a smaller dose (30 micrograms) than the Moderna booster (50 micrograms). This could conceivably cut down on side effects, Poland says, while still providing a very strong immune response. He says he plans to do just this for his booster. It's also possible, some experts say, that people who had the Pfizer shots initially will want to chase them with the Moderna booster precisely because the Moderna dose is higher than Pfizer's — with the idea that this might produce a bigger boost in antibodies.<<<

Editorial comment: Referring to the booster as a chaser shot does make it more appealing! (I suppose one could have Corona followed by a Moderna chaser shot?)

What you need to know about COVID boosters

You've seen the headlines about COVID boosters. But what does it all mean for you? Here's how to sort through the science and figure out if and when you need a booster and which one to get.

www.npr.org

Here are the mRNA doses in the first two Pfizer and Moderna shots:

>>>Each dose of the Pfizer/BioNTech vaccine delivers 30 µg of mRNA, while each of Moderna’s contains 100 µg.<<<

https://www.the-scientist.com/news-opinion/moderna-vs-pfizer-is-there-a-best-mrna-vaccine-69229

Assuming these reports are accurate, the Pfizer booster has the same amount of mRNA as the first two Pfizer shots, but the Moderna booster has one-half of the first two Moderna shots.

Assuming I'm eligible for a booster at some point, I'm going to try to get the Moderna booster (my first two were Pfizer) on the theory that more is always better (carrying over my approach to subwoofers), but I do wonder if 50 vs 30 micrograms really makes much difference.

 

[Swerd]

Oh boy I wonder why that seems to be the case? Did you mix vaccine shots between original and booster?

The wide range of reactions & timing that people typically feel early after getting the shot are all considered normal. The flu-like reactions (fever and general feeling of malaise) are brought on by how much interferon gets produced by the first-line non-specific immune cells.

These non-specific immune cells are like the local police or fire squad. They notice the virus proteins as something not normal, and they send out the alarm (they secrete interferon) to call in the specialized cells that make up the specific immune system. Interferon is a cytokine protein that both causes fever, and calls in more specialized immune cells.

In this case the local police/firemen also act as garbage collectors or crime scene investigators. They gather up the suspected virus bits & pieces and show them to the specific immune cells. With a primary vaccination, the specific immune cells don't exist until about 2 weeks after the shot. With subsequent shots, these cells are ready and waiting for the call.

 

[Swerd]

Each dose of the Pfizer/BioNTech vaccine delivers 30 µg of mRNA, while each of Moderna’s contains 100 µg.

Assuming I'm eligible for a booster at some point, I'm going to try to get the Moderna booster (my first two were Pfizer) on the theory that more is always better (carrying over my approach to subwoofers), but I do wonder if 50 vs 30 micrograms really makes much difference.

As always, it isn't quite so simple. It not only depends on how much mRNA is initially injected, but also how long that injected mRNA hangs around producing Spike protein molecules.

Those 2 vaccines have a number of features designed to prevent the injected mRNA from being rapidly degraded. Some of the features are direct chemical modifications of the mRNA that slow down it's degradation, and others are separate chemicals mixed in with the mRNA for the same purpose. The details of those features are carefully guarded trade secrets, and almost certainly Pfizer's differ from Moderna's. That may be the reason why the Pfizer vaccine has less mRNA than Moderna's – Pfizer's modifications & additives allow the mRNA to hang around longer than Moderna's.

 

[Kvn_Walker]

I got my Pfizer booster a couple weeks ago. Just had a sore arm for a couple days.