Does your 14/4 look like this?
If so, you have in-wall speaker cable capable of running signal to up to two speakers. It's covered by a plastic jacket, but there is no shielding. The four colored wires may be twisted together, but that isn't for noise rejection, it's to make it easier to pull the bundle through holes in studs or dry wall.
If you want to twist wires together to wire one speaker, it doesn't matter which wires you twist together as long as you twist the same colors together on each end of the cable.